Northern Iowa 24-42 Iowa State 2017-09-03 00:00
Stadium: Jack Trice Stadium Round: 1
Head to Head
| NCAAF | 2016/09/04 00:00 | Iowa State v Northern Iowa | W | 20-25 |
| NCAAF | 2015/09/06 00:00 | Iowa State v Northern Iowa | L | 31-7 |
| NCAAF | 2011/09/03 12:00 | Iowa State v Northern Iowa | L | 20-19 |
| NCAAF | 2010/09/25 12:00 | Iowa State v Northern Iowa | L | 27-0 |
| NCAAF | 2007/09/08 12:00 | Iowa State v Northern Iowa | W | 13-24 |
| NCAAF | 2006/09/30 12:00 | Iowa State v Northern Iowa | L | 28-27 |
| NCAAF | 2004/09/04 12:00 | Iowa State v Northern Iowa | L | 23-0 |
| NCAAF | 2003/08/30 12:00 | Iowa State v Northern Iowa | L | 17-10 |
Home History
| NCAAF | 2016/09/04 00:00 | Iowa State v Northern Iowa | W | 20-25 |
| NCAAF | 2015/12/12 17:00 | North Dakota State v Northern Iowa | L | 23-13 |
| NCAAF | 2015/12/06 03:00 | Portland State v Northern Iowa | W | 17-29 |
| NCAAF | 2015/11/28 22:00 | Northern Iowa v Eastern Illinois | W | 53-17 |
| NCAAF | 2015/09/06 00:00 | Iowa State v Northern Iowa | L | 31-7 |
| NCAAF | 2014/12/06 19:00 | Illinois State v Northern Iowa | L | 41-21 |
| NCAAF | 2014/11/30 01:00 | Northern Iowa v Stephen F. Austin | W | 44-10 |
| NCAAF | 2014/09/14 04:00 | Hawaii v Northern Iowa | L | 27-24 |
Away History
| NCAAF | 2016/11/26 20:30 | West Virginia v Iowa State | L | 49-19 |
| NCAAF | 2016/11/19 20:30 | Texas Tech v Iowa State | W | 10-66 |
| NCAAF | 2016/11/12 17:00 | Iowa State v Kansas | W | 31-24 |
| NCAAF | 2016/11/03 23:30 | Oklahoma v Iowa State | L | 34-24 |
| NCAAF | 2016/10/29 16:00 | Kansas State v Iowa State | L | 31-26 |
| NCAAF | 2016/10/15 23:00 | Iowa State v Texas | L | 6-27 |
| NCAAF | 2016/10/08 19:30 | Iowa State v Oklahoma State | L | 31-38 |
| NCAAF | 2016/10/01 16:00 | Baylor v Iowa State | L | 45-42 |