Stadium: Gate City Bank Field at the Fargodome Round: 1
Home Manager: Matt Entz Away Manager: Curt Cignetti
| NCAAF | 2020/01/11 17:00 | James Madison v North Dakota State | L | 20-28 |
| NCAAF | 2018/01/06 18:00 | North Dakota State v James Madison | L | 17-13 |
| NCAAF | 2016/12/17 00:00 | James Madison v North Dakota State | W | 27-17 |
| NCAAF | 2021/12/11 00:00 | Montana v James Madison | W | 6-28 |
| NCAAF | 2021/12/04 19:00 | SE Louisiana v James Madison | W | 20-59 |
| NCAAF | 2021/11/20 19:00 | Towson v James Madison | W | 10-56 |
| NCAAF | 2021/11/13 20:30 | James Madison v William & Mary | W | 32-22 |
| NCAAF | 2021/11/06 19:30 | Campbell v James Madison | W | 14-51 |
| NCAAF | 2021/10/30 18:00 | Elon v James Madison | W | 21-45 |
| NCAAF | 2021/10/23 19:00 | James Madison v Delaware | W | 22-10 |
| NCAAF | 2021/10/16 18:00 | James Madison v Richmond | W | 19-3 |
| NCAAF | 2021/12/11 17:00 | East Tennessee State v North Dakota State | W | 3-27 |
| NCAAF | 2021/12/04 20:30 | SO Illinois v North Dakota State | W | 7-38 |
| NCAAF | 2021/11/20 20:30 | South Dakota v North Dakota State | W | 24-52 |
| NCAAF | 2021/11/13 17:00 | North Dakota State v Youngstown State | W | 49-17 |
| NCAAF | 2021/11/06 19:00 | North Dakota State v South Dakota State | L | 19-27 |
| NCAAF | 2021/10/30 19:30 | Indiana State v North Dakota State | W | 2-44 |
| NCAAF | 2021/10/23 19:30 | Missouri St v North Dakota State | W | 20-27 |
| NCAAF | 2021/10/16 19:00 | North Dakota State v Illinois State | W | 20-0 |