[8] Southern Miss 27-24 Tulane [8] 2022-09-24 23:00
Stadium: Yulman Stadium Round: 1
Home Manager: Willie Fritz Away Manager: Will Hall
Head to Head
| NCAAF | 2020/09/26 18:30 | Tulane v Southern Mississippi | L | 66-24 |
| NCAAF | 2020/01/04 16:30 | Tulane v Southern Mississippi | L | 30-13 |
| NCAAF | 2010/11/06 12:00 | Tulane v Southern Mississippi | W | 30-46 |
| NCAAF | 2009/10/24 12:00 | Southern Mississippi v Tulane | W | 43-6 |
| NCAAF | 2006/11/11 12:00 | Tulane v Southern Mississippi | W | 3-31 |
| NCAAF | 2005/11/26 12:00 | Southern Mississippi v Tulane | W | 26-7 |
| NCAAF | 2004/09/25 12:00 | Tulane v Southern Mississippi | W | 14-32 |
| NCAAF | 2003/11/15 12:00 | Southern Mississippi v Tulane | W | 28-14 |
Home History
| NCAAF | 2022/09/17 23:00 | Northwestern State v Southern Mississippi | W | 10-64 |
| NCAAF | 2022/09/10 16:00 | Southern Mississippi v Miami Florida | L | 7-30 |
| NCAAF | 2022/09/03 23:00 | Libertay v Southern Mississippi | L | 29-27 |
| NCAAF | 2021/11/27 20:00 | Florida Intl v Southern Mississippi | W | 17-37 |
| NCAAF | 2021/11/20 01:00 | Southern Mississippi v Louisiana Tech | W | 35-19 |
| NCAAF | 2021/11/13 20:30 | Southern Mississippi v Texas-San Antonio | L | 17-27 |
| NCAAF | 2021/11/06 19:00 | North Texas v Southern Mississippi | L | 38-14 |
| NCAAF | 2021/10/30 19:30 | Southern Mississippi v Middle Tennessee St. | L | 10-35 |
Away History
| NCAAF | 2022/09/17 19:00 | Tulane v Kansas State | W | 17-10 |
| NCAAF | 2022/09/10 23:00 | Alcorn State v Tulane | W | 0-52 |
| NCAAF | 2022/09/03 23:00 | Massachusetts v Tulane | W | 10-42 |
| NCAAF | 2021/11/28 00:30 | Tulane v Memphis | L | 28-33 |
| NCAAF | 2021/11/20 17:00 | South Florida v Tulane | W | 14-45 |
| NCAAF | 2021/11/13 21:00 | Tulsa v Tulane | L | 20-13 |
| NCAAF | 2021/11/06 20:00 | Tulane v Central Florida | L | 10-14 |
| NCAAF | 2021/10/30 16:00 | Cincinnati v Tulane | L | 31-12 |