[7] River Plate Asuncion 2-1 Guairena FC [6] 2020-08-12 20:00
Stadium: Estadio River Plate Round: 13
Referee: Jose Mendez Home Manager: Celso Rafael Ayala Gavilan Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguayi Division Profesional | 2020/01/25 21:00 | Guairena FC v River Plate Asuncion | L | 2-0 |
| Paraguay Division Intermedia | 2018/07/29 13:30 | Guairena FC v River Plate Asuncion | L | 3-0 |
| Paraguay Division Intermedia | 2018/04/21 13:30 | River Plate Asuncion v Guairena FC | W | 3-1 |
| Paraguay Division Intermedia | 2017/06/24 14:00 | River Plate Asuncion v Guairena FC | D | 1-1 |
| Paraguay Division Intermedia | 2017/03/19 19:30 | Guairena FC v River Plate Asuncion | L | 1-0 |