[2] Cincinnati 45-28 South Florida [115] 2021-11-12 23:00
Stadium: Raymond James Stadium Round: 1
Home Manager: Jeff Scott Away Manager: Luke Fickell
Head to Head
| NCAAF | 2020/10/03 19:30 | South Florida v Cincinnati | W | 7-28 |
| NCAAF | 2019/11/17 00:00 | Cincinnati v South Florida | W | 20-17 |
| NCAAF | 2018/11/11 00:00 | South Florida v Cincinnati | W | 23-35 |
| NCAAF | 2017/10/14 23:30 | Cincinnati v South Florida | L | 3-33 |
| NCAAF | 2016/10/01 23:00 | South Florida v Cincinnati | L | 45-20 |
| NCAAF | 2015/11/21 01:00 | South Florida v Cincinnati | L | 65-27 |
| NCAAF | 2014/10/24 23:00 | Cincinnati v South Florida | W | 34-17 |
| NCAAF | 2012/11/23 12:00 | Cincinnati v South Florida | W | 27-10 |
| NCAAF | 2011/10/22 12:00 | South Florida v Cincinnati | W | 34-37 |
| NCAAF | 2010/10/22 12:00 | Cincinnati v South Florida | L | 30-38 |
| NCAAF | 2009/10/15 12:00 | South Florida v Cincinnati | W | 17-34 |
| NCAAF | 2008/10/30 12:00 | Cincinnati v South Florida | W | 24-10 |
| NCAAF | 2007/11/03 12:00 | South Florida v Cincinnati | W | 33-38 |
| NCAAF | 2006/10/22 12:00 | Cincinnati v South Florida | W | 23-6 |
| NCAAF | 2005/11/19 12:00 | South Florida v Cincinnati | L | 31-16 |
| NCAAF | 2004/11/20 12:00 | Cincinnati v South Florida | W | 45-23 |
| NCAAF | 2003/10/31 12:00 | South Florida v Cincinnati | L | 24-17 |