Texas Tech 14-10 Iowa State 2022-11-20 00:00
Stadium: Jack Trice Stadium Round: 1
Home Manager: Matt Campbell Away Manager: Joey McGuire
Head to Head
| NCAAF | 2021/11/13 20:30 | Iowa State v Texas Tech | W | 38-41 |
| NCAAF | 2020/10/10 19:30 | Texas Tech v Iowa State | L | 15-31 |
| NCAAF | 2019/10/19 16:00 | Iowa State v Texas Tech | L | 34-24 |
| NCAAF | 2018/10/27 16:00 | Texas Tech v Iowa State | L | 31-40 |
| NCAAF | 2017/10/21 16:00 | Iowa State v Texas Tech | L | 31-13 |
| NCAAF | 2016/11/19 20:30 | Texas Tech v Iowa State | L | 10-66 |
| NCAAF | 2015/10/10 19:30 | Texas Tech v Iowa State | W | 66-31 |
| NCAAF | 2014/11/22 20:30 | Iowa State v Texas Tech | W | 31-34 |
| NCAAF | 2012/09/29 12:00 | Iowa State v Texas Tech | W | 13-24 |
| NCAAF | 2011/10/29 12:00 | Texas Tech v Iowa State | L | 7-41 |
| NCAAF | 2010/10/02 12:00 | Iowa State v Texas Tech | L | 52-38 |
| NCAAF | 2007/10/06 12:00 | Texas Tech v Iowa State | W | 42-17 |
| NCAAF | 2006/10/21 12:00 | Iowa State v Texas Tech | W | 26-42 |
| NCAAF | 2003/10/11 12:00 | Texas Tech v Iowa State | W | 52-21 |
| NCAAF | 2002/10/12 12:00 | Iowa State v Texas Tech | L | 31-17 |